Adrenomedullin (1-50) (Rat) - RIA Kit

Catalog #
RK-010-08 125 tubes $588

  • Protocol:
  • View/Download (PDF) - for reference only
  • Sample Preparation:
  • Suggested Procedure
  • Sample Extraction:
  • Recommended
  • Sensitivity: polaroid
    Data may differ slightly based on lot.
  • 174.5 pg/ml
  • Standard Range:
  • 100 - 12800 pg/ml
  • Cross Reactivity:
  • Peptide %
    Adrenomedullin (Rat) 100
    Adrenomedullin (Human) 0
    Pro-Adrenomedullin N20 (Human) 0
    Pro-Adrenomedullin N20 (Rat) 0
    Amylin (Human) 0
    ET-1 (Human, Bovine, Canine, Mouse, Porcine, Rat) 0
    CGRP (Rat) 0
    Calcitonin (Rat) 0
    Calcitonin (Salmon) 0

  • Radioactivity:
  • Each kit contains 1.5 µCi of Iodine 125.
  • Disclaimer:
  • This package conforms to the 49 CFR173.421 for expected radioactive material limited quantity, N.O.S. UN2910.

Bell et al. Influence of atenolol and nifedipine on nitric-oxide deficient cardiomyocyte hypertrophy and expression of the cardio-endocrine peptide intermedin and its receptor components.
Cell Physiol Biochem. 2008;21(1-3):203-14.

Gupta et al. Activated protein C suppresses adrenomedullin and ameliorates lipopolysaccharide-induced hypotension.
Shock. 2007 Oct;28(4):468-76.

Qi et al. Chronic administration of adrenomedullin attenuates hypoxic pulmonary vascular structural remodeling and inhibits proadrenomedullin N-terminal 20-peptide production in rats
Peptides. 2007 Apr;28(4):910-9.

Dschietziq et al. Hypoxic Induction of Receptor Activity-Modifying Protein 2 Alters Regulation of Pulmonary Endothelin-1 by Adrenomedullin: Induction under Normoxia Versus Inhibition under Hypoxia
J Pharmacol Exp Ther. 2007 Apr;321(1):409-19.

Bell et al. Differential Effects of an Anti-Oxidant Intervention on Cardiomyocyte Expression of Adrenomedullin and Intermedin and their Receptor Components in Chronic Nitric Oxide Deficiency
Cell Physiol Biochem. 2007;20(5):269-82.

Fukai et al. Concomitant expression of adrenomedullin and its receptor components in rat adipose tissues.
Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E56-62

Jiang et al. Effects of adrenomedullin on aldosterone-induced cell proliferation in rat cardiac fibroblasts.
Biochim Biophys Acta. 2004 Nov 5;1690(3):265-75.

Jiang et al. Effects of adrenomedullin on cell proliferation in rat adventitia induced by aldosterone.
J Hypertens. 2004 Oct;22(10):1953-61.

Zhong et al. Effects of cobalt-60 gamma-radiation on the synthesis of adrenomedullin and endothelin in rat vascular smooth muscle cells.
Heart Vessels. 2003 Sep;18(4):207-12.

Neri et al. Simulated microgravity impairs aldosterone secretion in rats: possible involvement of adrenomedullin.
Am J Physiol Regul Integr Comp Physiol. 2002 Oct;283(4):R832-6.

Qi et al. Adrenomedullin inhibits the endothelin production induced by urotensin II in rat vascular smooth muscle cells
Chin. Sci Bul. 2002 Sep 17;47(17):1457-61. (PDF)

Stangl et al. Pulmonary adrenomedullin counteracts deterioration of coronary flow and myocardial performance evoked by pulmonary endothelins in experimental acute respiratory distress syndrome.
Crit Care Med. 2001 May;29(5):1027-32.

Samson et al. Antisense oligonucleotide treatment reveals a physiologically relevant role for adrenomedullin gene products in sodium intake.
Brain Res. 1999 Feb 6;818(1):164-7.

Hofbauer - AJP - Regl. - Integ. & Compar. Physio. Vol. 278 - Issue 2 - R513-R519 - February 2000