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Adrenomedullin (22-52) (Human)

Quantity:

Catalog #
Size
Price
010-04 100 µg $180

Sequence:  ()
Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2
  • Molecular Weight:
  • 3576.03
  • Purity:
  • ≥ 95%
  • Validation:
  • Exhibits correct molecular weight
  • Solubility:
  • Soluble in water
  • Storage:
  • Up to 6 months in lyophilized form at 0-5°C.
    For best results, rehydrate just before use.
    After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
  • Appearance:
  • White powder
  • Contents:
  • Each vial contains 100 µg of NET peptide.
  • MSDS:
  • View/Download(PDF)

Adrenomedullin expression in epithelial ovarian cancers and promotes HO8910 cell migration associated with upregulating integrin α5β1 and phosphorylating FAK and paxillin. 

Upregulated expression of intermedin and its receptor in the myocardium and aorta in spontaneously hypertensive rats.

Interaction ofadrenomedullin and calcitonin gene-related peptide with the periodontal pathogen Porphyromonas gingivalis.

The myocardial response to adrenomedullin involves increased cAMP generation as well as augmented Akt phosphorylation.

Mechanisms of adrenomedullin antimicrobial action.
Allaker RP, Grosvenor PW, Mcanerney DC, et al. Peptides. 2006;27(4):661-6.

Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis.

Intermedin 1-53 in central nervous system elevates arterial blood pressure in rats.

Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue.

Effects of adrenomedullin on cell proliferation in rat adventitia induced by aldosterone.

Adrenomedullin receptor binding sites in rat brain and peripheral tissues.

Saturation of adrenomedullin receptors plays an important role in reducing pulmonary clearance of adrenomedullin during the late stage of sepsis.

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