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BNP-32 (Canine)

Quantity:

Catalog #
Size
Price
011-22 200 µg $135

Sequence:  ()
Ser-Pro-Lys-Met-Met-His-Lys-Ser-Gly-Cys-Phe-Gly-Arg-Arg-Leu-Asp-Arg-Ile-Gly-Ser-Leu-Ser-Gly-Leu-Gly-Cys-Asn-Val-Leu-Arg-Lys-Tyr
Disulfide bridge(s): Cys10-Cys26
  • Molecular Weight:
  • 3566.29
  • Purity:
  • ≥ 95%
  • Validation:
  • Exhibits correct molecular weight
  • Solubility:
  • Soluble in water
  • Storage:
  • Up to 6 months in lyophilized form at 0-5°C.
    For best results, rehydrate just before use.
    After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
  • Appearance:
  • White powder
  • Contents:
  • Each vial contains 200 µg of NET peptide.
  • MSDS:
  • View/Download

Analytical validation of commercial immunoassays for the measurement of cardiovascular peptides in the dog.
Schellenberg S, Grenacher B, Kaufmann K, Reusch CE, Glaus TM. Vet J. 2008;178(1):85-90.

Acute phosphodiesterase 5 inhibition mimics hemodynamic effects of B-type natriuretic peptide and potentiates B-type natriuretic peptide effects in failing but not normal canine heart.
Forfia PR, Lee M, Tunin RS, Mahmud M, Champion HC, Kass DA. J Am Coll Cardiol. 2007;49(10):1079-88.

Maximizing the renal cyclic 3'-5'-guanosine monophosphate system with type V phosphodiesterase inhibition and exogenous natriuretic peptide: a novel strategy to improve renal function in experimental overt heart failure.
Chen HH, Huntley BK, Schirger JA, Cataliotti A, Burnett JC. J Am Soc Nephrol. 2006;17(10):2742-7.

Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases.
Tsuruda T, Boerrigter G, Huntley BK, et al. Circ Res. 2002;91(12):1127-34.

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