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Urocortin (Human)

Quantity:

Catalog #
Size
Price
019-14 100 µg $168

Sequence:  ()
Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2
  • Molecular Weight:
  • 4696.31
  • Purity:
  • ≥ 95%
  • Validation:
  • Exhibits correct molecular weight
  • Solubility:
  • Insoluble in water.
    Dissolve in a small amount of 60% acetonitrile in water with 0.1% TFA. Then dilute with water or any desired buffer.
  • Storage:
  • Up to 6 months in lyophilized form at 0-5°C.
    For best results, rehydrate just before use.
    After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
  • Appearance:
  • White powder
  • Contents:
  • Each vial contains 100 µg of NET peptide.

Endothelial urocortin has potent antioxidative properties and is upregulated by inflammatory cytokines and pitavastatin.
Honjo T, Inoue N, Shiraki R, et al. J Vasc Res. 2006;43(2):131-8.

Intracellular calcium measurements of single human skin cells after stimulation with corticotropin-releasing factor and urocortin using confocal laser scanning microscopy.
Wiesner B, Roloff B, Fechner K, Slominski A. J Cell Sci. 2003;116(Pt 7):1261-8.

Vasodilator actions of urocortin and related peptides in the human perfused placenta in vitro.
Leitch IM, Boura AL, Botti C, Read MA, Walters WA, Smith R. J Clin Endocrinol Metab. 1998;83(12):4510-3.

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