Catalog # |
Size |
Price |
|
|---|---|---|---|
| 021-55 | 500 µg | $128 |
)
|
Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln
|
| 1809.06 | |
|
| ≥ 95% |
|
| Exhibits correct molecular weight |
|
| Soluble in water |
|
|
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles. |
|
| White powder |
|
| Each vial contains 500 µg of NET peptide. |
Neuropeptide orphanin FQ inhibits dendritic morphogenesis through activation of RhoA.
Alder J, Kallman S, Palmieri A, et al. Dev Neurobiol. 2013;73(10):769-84.
Roles of the bed nucleus of stria terminalis and of the amygdala in N/OFQ-mediated anxiety and HPA axis activation.
Green MK, Barbieri EV, Brown BD, Chen KW, Devine DP. Neuropeptides. 2007;41(6):399-410.
Identification of central nervous system sites involved in the water diuresis response elicited by central microinjection of nociceptin/ Orphanin FQ in conscious rats via c-Fos and inducible cAMP early repressor immunocytochemistry.
Gottlieb HB, Fleming TM, Ji L, Cunningham JT. J Neuroendocrinol. 2007;19(7):531-42.
Anti-nociceptive and anti-allodynic effects of a high affinity NOP hexapeptide [Ac-RY(3-Cl)YRWR-NH2] (Syn 1020) in rodents.
Khroyan TV, Polgar WE, Orduna J, et al. Eur J Pharmacol. 2007;560(1):29-35.
Functional interaction between nociceptin/orphanin FQ and alpha-melanocyte-stimulating hormone in the regulation of feeding.
Bomberg EM, Grace MK, Levine AS, Olszewski PK. Peptides. 2006;27(7):1827-34.
Tonic nociceptinergic inputs to neurons in the hypothalamic paraventricular nucleus contribute to sympathetic vasomotor tone and water and electrolyte homeostasis in conscious rats.
Krowicki ZK, Kapusta DR. J Pharmacol Exp Ther. 2006;317(1):446-53.
Transcriptional profiling of brain-derived-neurotrophic factor-induced neuronal plasticity: a novel role for nociceptin in hippocampal neurite outgrowth.
Ring RH, Alder J, Fennell M, Kouranova E, Black IB, Thakker-varia S. J Neurobiol. 2006;66(4):361-77.
Differential activation of ERK, p38, and JNK MAPK by nociceptin/orphanin FQ in the potentiation of prostaglandin cerebrovasoconstriction after brain injury.
Armstead WM. Eur J Pharmacol. 2006;529(1-3):129-35.
Baclofen inhibits guinea pig magnocellular neurones via activation of an inwardly rectifying K+ conductance.
Slugg RM, Zheng SX, Fang Y, Kelly MJ, Rønnekleiv OK. J Physiol (Lond). 2003;551(Pt 1):295-308.
Nociceptin/orphanin FQ inhibits capsaicin-induced guinea-pig airway contraction through an inward-rectifier potassium channel.
Jia Y, Wang X, Aponte SI, et al. Br J Pharmacol. 2002;135(3):764-70.
Comparison of pharmacological activities of buprenorphine and norbuprenorphine: norbuprenorphine is a potent opioid agonist.
Huang P, Kehner GB, Cowan A, Liu-chen LY. J Pharmacol Exp Ther. 2001;297(2):688-95.
Cutting edge: nociceptin stimulates neutrophil chemotaxis and recruitment: inhibition by aspirin-triggered-15-epi-lipoxin A4.
Serhan CN, Fierro IM, Chiang N, Pouliot M. J Immunol. 2001;166(6):3650-4.
Accelerated release and production of orphanin FQ in brain of chronic morphine tolerant rats.
Yuan L, Han Z, Chang JK, Han JS. Brain Res. 1999;826(2):330-4.
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