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KiSS-1 (112-121) amide / Kisspeptin-10 / Metastin (45-54) amide (Human)

Quantity:

Catalog #
Size
Price
048-56 200 µg $82

Sequence:  ()
Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
  • Molecular Weight:
  • 1302.44
  • Purity:
  • ≥ 95%
  • Validation:
  • Exhibits correct molecular weight
  • Solubility:
  • Soluble in water
  • Storage:
  • Up to 6 months in lyophilized form at 0-5°C.
    For best results, rehydrate just before use.
    After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
  • Appearance:
  • White powder
  • Contents:
  • Each vial contains 200 µg of NET peptide.

Intratesticular action of kisspeptin in rhesus monkey (Macaca mulatta).
Irfan S, Ehmcke J, Wahab F, Shahab M, Schlatt S. Andrologia. 2014;46(6):610-7.

FGF21 contributes to neuroendocrine control of female reproduction.
Owen BM, Bookout AL, Ding X, et al. Nat Med. 2013;19(9):1153-6.

Evidence for a celiac ganglion-ovarian kisspeptin neural network in the rat: intraovarian anti-kisspeptin delays vaginal opening and alters estrous cyclicity.
Ricu MA, Ramirez VD, Paredes AH, Lara HE. Endocrinology. 2012;153(10):4966-77.

Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol.
Pielecka-fortuna J, Chu Z, Moenter SM. Endocrinology. 2008;149(4):1979-86.

Direct kisspeptin-10 stimulation on luteinizing hormone secretion from bovine and porcine anterior pituitary cells.
Suzuki S, Kadokawa H, Hashizume T. Anim Reprod Sci. 2008;103(3-4):360-5.

Neuroendocrine phenotype analysis in five patients with isolated hypogonadotropic hypogonadism due to a L102P inactivating mutation of GPR54.
Tenenbaum-rakover Y, Commenges-ducos M, Iovane A, Aumas C, Admoni O, De roux N. J Clin Endocrinol Metab. 2007;92(3):1137-44.

Environmental control of kisspeptin: implications for seasonal reproduction.
Greives TJ, Mason AO, Scotti MA, et al. Endocrinology. 2007;148(3):1158-66.

Suppression of kisspeptin expression and gonadotropic axis sensitivity following exposure to inhibitory day lengths in female Siberian hamsters.
Mason AO, Greives TJ, Scotti MA, et al. Horm Behav. 2007;52(4):492-8.

Characteristic of hypothalamic kisspeptin expression in the pubertal development of precocious female rats.
Sun Y, Tian Z, Zhao H, Wong ST, Chen B. Neurosci Lett. 2007;420(1):12-7.

Colocalization of kisspeptin and gonadotropin-releasing hormone in the ovine brain.
Pompolo S, Pereira A, Estrada KM, Clarke IJ. Endocrinology. 2006;147(2):804-10.

Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats.
Castellano JM, Navarro VM, Fernández-fernández R, et al. Diabetes. 2006;55(9):2602-10.

Cancer metastasis-suppressing peptide metastin upregulates excitatory synaptic transmission in hippocampal dentate granule cells.
Arai AC, Xia YF, Suzuki E, Kessler M, Civelli O, Nothacker HP. J Neurophysiol. 2005;94(5):3648-52.

Two novel missense mutations in g protein-coupled receptor 54 in a patient with hypogonadotropic hypogonadism.
Semple RK, Achermann JC, Ellery J, et al. J Clin Endocrinol Metab. 2005;90(3):1849-55.

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