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Adrenomedullin (22-52) (Human)

Catalog No. 010-04

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Catalog #: 010-04

Size: 100 µg

Price: $233

Sequence:	Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2
Molecular Weight:	3576.03
Purity:	≥ 95%
Validation:	Exhibits correct molecular weight
Solubility:	Soluble in water
Storage:	Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Appearance:	White powder
Contents:	Each vial contains 100 µg of NET peptide.

Adrenomedullin expression in epithelial ovarian cancers and promotes HO8910 cell migration associated with upregulating integrin α5β1 and phosphorylating FAK and paxillin.

Deng, Boya et al., Journal of Experimental & Clinical Cancer Research, March 9, 2012

Upregulated expression of intermedin and its receptor in the myocardium and aorta in spontaneously hypertensive rats.

Zeng et al. Peptides. 2009 Feb;30(2):391-9.

Interaction ofadrenomedullin and calcitonin gene-related peptide with the periodontal pathogen Porphyromonas gingivalis.

Allaker et al. FEMS Immunol Med Microbiol. 2007 Feb;49(1):91-7.

The myocardial response to adrenomedullin involves increased cAMP generation as well as augmented Akt phosphorylation.

Pan et al. Peptides. 2007 Apr;28(4):900-9.

Mechanisms of adrenomedullin antimicrobial action.
Allaker RP, Grosvenor PW, Mcanerney DC, et al. Peptides. 2006;27(4):661-6.

Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis.

Zudaire et al. Am J Pathol. 2006 Jan;168(1):280-91.

Intermedin 1-53 in central nervous system elevates arterial blood pressure in rats.

Ren et al. Peptides. 2006 Jan;27(1):74-9.

Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue.

Linscheid et al. Endocrinology. 2005 Jun;146(6):2699-708.

Effects of adrenomedullin on cell proliferation in rat adventitia induced by aldosterone.

Jiang et al. J Hypertens. 2004 Oct;22(10):1953-61.

Adrenomedullin receptor binding sites in rat brain and peripheral tissues.

Juaneda et al. Eur J Pharmacol. 2003 Aug 8;474(2-3):165-74.

Saturation of adrenomedullin receptors plays an important role in reducing pulmonary clearance of adrenomedullin during the late stage of sepsis.

Ornan et al. Biochim Biophys Acta. 2002 Apr 24;1586(3):299-306.

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Peptide Family

Adrenomedullin

Species

Human

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Available only to verified institutional research accounts for in vitro laboratory research and preclinical studies.

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Adrenomedullin (22-52) (Human)

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