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Corticotropin Releasing Factor (CRF) (9-41), alpha-helical (Ovine)
Verified institutional research accounts only. Supplied for in vitro laboratory research and preclinical studies.
Peptides
Corticotropin Releasing Factor (CRF) (9-41), alpha-helical (Ovine)
Catalog No. 019-16
Catalog #: 019-16
Size: 200 µg
Price: $104
Sequence: Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH2 Molecular Weight: 3826.43 Purity: ≥ 95% Validation: Exhibits correct molecular weight Solubility: Insoluble in water. Storage: Up to 6 months in lyophilized form at 0-5°C. Appearance: White powder Contents: Each vial contains 200 µg of NET peptide.
In vivo administration of corticotropin-releasing hormone at remote intervals following ischemia enhances CA1 neuronal survival and recovery of spatial memory impairments: a role for opioid receptors. Charron C, Fréchette S, Proulx G, Plamondon H. Behav Brain Res. 2008;188(1):125-35.
Effects of in vivo and in vitro administration of ghrelin, leptin and neuropeptide mediators on pulsatile gonadotrophin-releasing hormone secretion from male rat hypothalamus before and after puberty. Lebrethon MC, Aganina A, Fournier M, Gérard A, Parent AS, Bourguignon JP. J Neuroendocrinol. 2007;19(3):181-8.
Corticotropin-releasing hormone receptor (CRHR)1 and CRHR2 are both trafficking and signaling receptors for urocortin. Tu H, Kastin AJ, Pan W. Mol Endocrinol. 2007;21(3):700-11.
The CRH1 antagonist CP154,526 failed to alter ischemia-induced neurodegeneration and spatial memory deficits in rats but inhibited behavioral activity in the novel open field. Plamondon H, Khan S. Behav Brain Res. 2006;166(1):85-92.
Prolactin-releasing peptide and its homolog RFRP-1 act in hypothalamus but not in anterior pituitary gland to stimulate stress hormone secretion. Samson WK, Keown C, Samson CK, et al. Endocrine. 2003;20(1-2):59-66.
Role of corticotrophin-releasing factor in effects of leptin on sympathetic nerve activity and arterial pressure. Correia ML, Morgan DA, Mitchell JL, Sivitz WI, Mark AL, Haynes WG. Hypertension. 2001;38(3):384-8.
Vasodilator actions of urocortin and related peptides in the human perfused placenta in vitro. Leitch IM, Boura AL, Botti C, Read MA, Walters WA, Smith R. J Clin Endocrinol Metab. 1998;83(12):4510-3.
Institutional Access
Available only to verified institutional research accounts for in vitro laboratory research and preclinical studies.
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