Cerebrospinal fluid irisin correlates with amyloid-β, BDNF, and cognition in Alzheimer's disease.
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A Polymorphism in the Irisin-encoding Gene (FNDC5) Associates With Hepatic Steatosis by Differential miRNA Binding to the 3'UTR
Metwally M, Bayoumi A, Romero-gomez M, et al. Journal of Hepatology 2019;70(3):494-500.
Circulating irisin levels in heart failure with preserved or reduced ejection fraction: A pilot study.
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Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models.
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Association of serum concentrations of irisin and the adipokines adiponectin and leptin with epicardial fat in cardiovascular surgery patients.
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Irisin Maternal Plasma and Cord Blood Levels in Mothers with Spontaneous Preterm and Term Delivery.
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Does high intensity exercise affects irisin plasma levels in hemodialysis patients? A pilot study.
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Retinoic Acid Increases Fatty Acid Oxidation and Irisin Expression in Skeletal Muscle Cells and Impacts Irisin In Vivo.
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Lower Serum Irisin Levels Are Associated with Increased Vascular Calcification in Hemodialysis Patients.
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Exercise-induced irisin release as a determinant of the metabolic response to exercise training in obese youth: the EXIT trial.
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Serum fatty acid-binding protein 4 (FABP4) concentration is associated with insulin resistance in peripheral tissues, A clinical study.
Serum irisin levels correlated to peritoneal dialysis adequacy in nondiabetic peritoneal dialysis patients.
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Irisin: A Potential Link between Physical Exercise and Metabolism-An Observational Study in Differently Trained Subjects, from Elite Athletes to Sedentary People.
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Plasma Irisin Modestly Increases during Moderate and High-Intensity Afternoon Exercise in Obese Females.
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Association of Serum Irisin Concentrations with Presence and Severity of Coronary Artery Disease.
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Effects of Body Weight Reduction on Serum Irisin and Metabolic Parameters in Obese Subjects.
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Circulating Levels of Irisin in Hypopituitary and Normal Subjects.
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High Serum Irisin Level as an Independent Predictor of Diabetes Mellitus: A Longitudinal Population-Based Study.
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Irisin Is Regulated by CAR in Liver and Is a Mediator of Hepatic Glucose and Lipid Metabolism.
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Irisin modulates the association of interleukin-17A with the presence of non-proliferative diabetic retinopathy in patients with type 2 diabetes.
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Time-dependent irisin concentration changes in patients affected by overt hypothyroidism.
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Circulating Adipocyte Fatty Acid Binding Protein (FABP4) Levels Are Associated with Irisin in the Middle-Aged General Chinese Population.
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Effects and Molecular Mechanism of GST-Irisin on Lipolysis and Autocrine Function in 3T3-L1 Adipocytes.
Gao S, Li F, Li H, Huang Y, Liu Y, Chen Y. PLoS ONE. 2016;11(1):e0147480.
Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes.
Liu TY, Shi CX, Gao R, et al. Clin Sci. 2015;129(10):839-50.
Betatrophin levels are increased in women with gestational diabetes mellitus compared to healthy pregnant controls.
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Circulating irisin is lower in gestational diabetes mellitus.
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Irisin in blood increases transiently after single sessions of intense endurance exercise and heavy strength training.
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Associations of betatrophin levels with irisin in Chinese women with normal glucose tolerance.
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Elevated circulating levels of irisin and the effect of metformin treatment in women with polycystic ovary syndrome.
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Plasma irisin in runners and nonrunners: no favorable metabolic associations in humans.
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Impact of supervised exercise rehabilitation on daily physical activity of cardiopulmonary patients.
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Complexity-Based Measures Inform Effects of Tai Chi Training on Standing Postural Control: Cross-Sectional and Randomized Trial Studies.
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Thermogenic capacity is antagonistically regulated in classical brown and white subcutaneous fat depots by high fat diet and endurance training in rats: impact on whole-body energy expenditure.
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Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans.
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Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans.
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The identification of irisin in human cerebrospinal fluid: influence of adiposity, metabolic markers, and gestational diabetes.
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Serum levels of irisin in gestational diabetes mellitus during pregnancy and after delivery.
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Plasma irisin depletion under energy restriction is associated with improvements in lipid profile in metabolic syndrome patients.
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Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?.
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Exercise training does not increase muscle FNDC5 protein or mRNA expression in pigs.
Fain JN, Company JM, Booth FW, et al. Metab Clin Exp. 2013;62(10):1503-11.
Resistance exercise training does not affect plasma irisin levels of hemodialysis patients.
Moraes C, Leal VO, Marinho SM, et al. Horm Metab Res. 2013;45(12):900-4.
Circulating irisin in relation to insulin resistance and the metabolic syndrome.
Park KH, Zaichenko L, Brinkoetter M, et al. J Clin Endocrinol Metab. 2013;98(12):4899-907.
Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies.
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The effects of acute and chronic exercise on PGC-1α, irisin and browning of subcutaneous adipose tissue in humans.
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