Verified institutional research accounts only. Supplied for in vitro laboratory research and preclinical studies.
Peptides
Relaxin 2 (Human) – 20µg
Catalog No. 035-62
Catalog #: 035-62
Size: 20 µg
Price: $264
Sequence: pGlu-Leu-Tyr-Ser-Ala-Leu-Ala-Asn-Lys-Cys-Cys-His-Val-Gly-Cys-Thr-Lys-Arg-Ser-Leu-Ala-Arg-Phe-Cys B-Chain: Asp-Ser-Trp-Met-Glu-Glu-Val-Ile-Lys-Leu-Cys-Gly-Arg-Glu-Leu-Val-Arg-Ala-Gln-Ile-Ala-Ile-Cys-Gly-Met-Ser-Thr-Trp-Ser Molecular Weight: 5963.06 Purity: ≥ 95% Validation: Exhibits correct molecular weight Solubility: Soluble in water Storage: Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles. Appearance: White powder Contents: Each vial contains 20 µg of NET peptide. Disulfide Bridge: Disulfide bridge(s): CysA10-CysA15, CysA11-CysB11, CysA24-CysB23
Relaxin in paraventricular nucleus contributes to sympathetic overdrive and hypertension via PI3K-Akt pathway. Sun HJ, Chen D, Han Y, et al. Neuropharmacology. 2016;103:247-56.
H2 and H3 relaxin inhibit high glucose-induced apoptosis in neonatal rat ventricular myocytes. Zhang X, Ma X, Zhao M, et al. Biochimie. 2015;108:59-67.
Relaxin affects cell organization and early and late stages of spermatogenesis in a coculture of rat testicular cells. Pimenta MT, Francisco RA, Silva RP, Porto CS, Lazari MF. Andrology. 2015;3(4):772-86.
Mesangial cells cultured from pregnant rats display reduced reactivity to angiotensin II: the role of relaxin, nitric oxide and AT2 receptor. Carvalho LN, Cristovam PC, Passos CS, Boim MA. Cell Physiol Biochem. 2012;30(6):1456-64.
The positive inotropic effect of relaxin-2 in human atrial myocardium is preserved in end-stage heart failure: role of G(i)-phosphoinositide-3 kinase signaling. Dschietzig T, Alexiou K, Kinkel HT, Baumann G, Matschke K, Stangl K. J Card Fail. 2011;17(2):158-66.
Relaxin stimulates osteoclast differentiation and activation. Ferlin A, Pepe A, Facciolli A, Gianesello L, Foresta C. Bone. 2010;46(2):504-13.
Autoregulation of human relaxin-2 gene expression critically involves relaxin and glucocorticoid receptor binding to glucocorticoid response half-sites in the relaxin-2 promoter. Dschietzig T, Bartsch C, Wessler S, Baumann G, Stangl K. Regul Pept. 2009;155(1-3):163-73.
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Available only to verified institutional research accounts for in vitro laboratory research and preclinical studies.
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