Melanin-Concentrating Hormone (MCH) (Human, Rat, Mouse) - Antibody


Catalog #
H-070-47 50 µl $225

  • Host:
  • Rabbit
  • Clonality:
  • Polyclonal
  • Protocol:
  • View/Download (PDF) - for reference only
  • Solubility:
  • Reconstitute with 50 µl of distilled water for the equivalent of undiluted antiserum.
  • Storage:
  • Please store the lyophilized antibody at -20°C upon receipt for up to 24 months. For optimal results, use the antibody immediately after reconstitution. Once reconstituted, the antibody is stable for up to three (3) days at 4°C. For longer-term storage up to three (3) months, prepare small aliquots of the reconstituted antibody and freeze at -20°C or -80°C. Repeated freeze-thaw cycles should be strictly avoided.
  • Contents:
  • Each vial contains 50 µl of lyophilized rabbit antiserum.

Nitric oxide mediates selective degeneration of hypothalamic orexin neurons through dysfunction of protein disulfide isomerase.
Obukuro K, Nobunaga M, Takigawa M, et al. J Neurosci. 2013;33(31):12557-68.

Novel variant of neuronal intranuclear rodlet immunoreactive for 40 kDa huntingtin associated protein and ubiquitin in the mouse brain.
Milman P, Woulfe J. J Comp Neurol. 2013;521(16):3832-46.

Immunohistochemical evidence for synaptic release of GABA from melanin-concentrating hormone containing varicosities in the locus coeruleus.
Del cid-pellitero E, Jones BE. Neuroscience. 2012;223:269-76.

Projections from the anterior basomedial and anterior cortical amygdaloid nuclei to melanin-concentrating hormone-containing neurons in the lateral hypothalamus of the rat.
Niu JG, Yokota S, Tsumori T, Oka T, Yasui Y. Brain Res. 2012;1479:31-43.

Synaptic alpha-dystrobrevin: localization of a short alpha-dystrobrevin isoform in melanin-concentrating hormone neurons of the hypothalamus.
Hazai D, Lien CF, Hajós F, Halasy K, Górecki DC, Jancsik V. Brain Res. 2008;1201:52-9.

Characterization of brainstem peptide YY (PYY) neurons.
Glavas MM, Grayson BE, Allen SE, et al. J Comp Neurol. 2008;506(2):194-210.

Peripheral ghrelin interacts with orexin neurons in glucostatic signalling.
Solomon A, De fanti BA, Martínez JA. Regul Pept. 2007;144(1-3):17-24.

Melanin concentrating hormone and estrogen receptor-alpha are coexstensive but not coexpressed in cells of male rat hypothalamus.
Muschamp JW, Hull EM. Neurosci Lett. 2007;427(3):123-6.

Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.
Tanabe A, Yanagiya T, Iida A, et al. J Clin Endocrinol Metab. 2007;92(3):1145-54.

Effects of serotonin on perifornical-lateral hypothalamic area neurons in rat.
Kumar S, Szymusiak R, Bashir T, Rai S, Mcginty D, Alam MN. Eur J Neurosci. 2007;25(1):201-12.

Differential c-Fos immunoreactivity in arousal-promoting cell groups following systemic administration of caffeine in rats.
Deurveilher S, Lo H, Murphy JA, Burns J, Semba K. J Comp Neurol. 2006;498(5):667-89.

Bidirectional dopaminergic modulation of excitatory synaptic transmission in orexin neurons.
Alberto CO, Trask RB, Quinlan ME, Hirasawa M. J Neurosci. 2006;26(39):10043-50.

Expression pattern of FOS in orexin neurons during sleep induced by an adenosine A2A receptor agonist.
Satoh S, Matsumura H, Kanbayashi T, et al. Behav Brain Res. 2006;170(2):277-86.

Hypothalamic and zona incerta neurons expressing hypocretin, but not melanin concentrating hormone, project to the hamster intergeniculate leaflet.
Vidal L, Blanchard J, Morin LP. Neuroscience. 2005;134(3):1081-90.

Central and peripheral immunoreactivity of melanin-concentrating hormone in hypothalamic obese and lactating rats.
Sun G, Tian Z, Murata T, Narita K, Honda K, Higuchi T. J Neuroendocrinol. 2004;16(1):79-83.

Ghrelin-induced food intake is mediated via the orexin pathway.
Toshinai K, Date Y, Murakami N, et al. Endocrinology. 2003;144(4):1506-12.

Neurochemical phenotype of hypothalamic neurons showing Fos expression 23 h after intracranial AgRP.
Zheng H, Corkern MM, Crousillac SM, Patterson LM, Phifer CB, Berthoud HR. Am J Physiol Regul Integr Comp Physiol. 2002;282(6):R1773-81.

Acute central ghrelin and GH secretagogues induce feeding and activate brain appetite centers.
Lawrence CB, Snape AC, Baudoin FM, Luckman SM. Endocrinology. 2002;143(1):155-62.

Melanin-concentrating hormone stimulates the release of luteinizing hormone-releasing hormone and gonadotropins in the female rat acting at both median eminence and pituitary levels.
Chiocchio SR, Gallardo MG, Louzan P, Gutnisky V, Tramezzani JH. Biol Reprod. 2001;64(5):1466-72.

Brain uncoupling protein 2: uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers.
Horvath TL, Warden CH, Hajos M, Lombardi A, Goglia F, Diano S. J Neurosci. 1999;19(23):10417-27.

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