Dynorphin A (Human, Rat, Mouse, Porcine) - RIA Kit


Catalog #
RK-021-03 125 tubes $776

  • Protocol:
  • View/Download (PDF) - for reference only
  • Sample Preparation:
  • Suggested Procedure
  • Sample Extraction:
  • Recommended
  • Sensitivity: polaroid
    Data may differ slightly based on lot.
  • 60 pg/ml
  • Standard Range:
  • 0.5-64 pg/tube in 100ul Standard Solution = 5-640 pg/ml
  • Cross Reactivity:
  • Peptide %
    Dynorphin A (Porcine) 100
    Dynorphin A (1-13) (Porcine) <1.0
    Dynorphin A (1-8) (Porcine) 0
    Dynorphin B (Porcine) 0
    β-Endorphin (Human) 0
    α-Neo-Endorphin (Porcine) 0
    Leu-Enkephalin 0

  • Radioactivity:
  • Each kit contains 1.5 µCi of Iodine 125.
  • Disclaimer:
  • This package conforms to the 49 CFR173.421 for expected radioactive material limited quantity, N.O.S. UN2910.
  • MSDS:
  • View/Download(PDF)

Analgesic roles of peripheral intrinsic met-enkephalin and dynorphin A in long-lasting inflammatory pain induced by complete Freund's adjuvant in rats.
YONG-LIANG JIANG, XIAO-FEN HE, YA-FANG SHEN et al., Exp Ther Med. 2015 Jun; 9(6): 2344–2348.

The social defeat animal model of depression shows diminished levels of orexin in mesocortical regions of the dopamine system, and of dynorphin and orexin in the hypothalamus.
Nocjar C, Zhang J, Feng P, Panksepp J. Neuroscience. 2012;218:138-53.

Cathepsin H functions as an aminopeptidase in secretory vesicles for production of enkephalin and galanin peptide neurotransmitters.
Lu WD, Funkelstein L, Toneff T, Reinheckel T, Peters C, Hook V. J Neurochem. 2012;122(3):512-22.

Decreased dynorphin A (1-17) in the spinal cord of spastic rats after the compressive injury.
Hong-Wei Dong et al., Brain Research Bulletin (impact factor: 2.82). 11/2005; 67(3):189-95. DOI:10.1016/j.brainresbull.2005.06.026 

Striatal opioid peptide content in an animal model of spontaneous stereotypic behavior.
Presti MF, Lewis MH. Behav Brain Res. 2005;157(2):363-8.

Reduction of opioid dependence by the CB(1) antagonist SR141716A in mice: evaluation of the interest in pharmacotherapy of opioid addiction.
Mas-nieto M, Pommier B, Tzavara ET, et al. Br J Pharmacol. 2001;132(8):1809-16.