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INSL7 / Relaxin 3 (Human)

Quantity:

Catalog #
Size
Price
035-36 20 µg $152

Sequence:  ()
A Chain:
Asp-Val-Leu-Ala-Gly-Leu-Ser-Ser-Ser-Cys-Cys-Lys-Trp-Gly-Cys-Ser-Lys-Ser-Glu-Ile-Ser-Ser-Leu-Cys
B Chain:
Arg-Ala-Ala-Pro-Tyr-Gly-Val-Arg-Leu-Cys-Gly-Arg-Glu-Phe-Ile-Arg-Ala-Val-Ile-Phe-Thr-Cys-Gly-Gly-Ser-Arg-Trp
Disulfide bridge(s): CysA10-CysA15, CysA11-CysB10, CysA24-CysB22
  • Molecular Weight:
  • 5500.49
  • Purity:
  • ≥ 95%
  • Validation:
  • Exhibits correct molecular weight
  • Solubility:
  • Soluble in water
  • Storage:
  • Up to 6 months in lyophilized form at 0-5°C.
    For best results, rehydrate just before use.
    After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
  • Appearance:
  • White powder
  • Contents:
  • Each vial contains 20 µg of NET peptide.
  • MSDS:
  • View/Download(PDF)

Relaxin-3 stimulates the hypothalamic-pituitary-gonadal axis.
Mcgowan BM, Stanley SA, Donovan J, et al. Am J Physiol Endocrinol Metab. 2008;295(2):E278-86.

The insulin-like growth factor type 1 and insulin-like growth factor type 2/mannose-6-phosphate receptors independently regulate ERK1/2 activity in HEK293 cells.
El-shewy HM, Lee MH, Obeid LM, Jaffa AA, Luttrell LM. J Biol Chem. 2007;282(36):26150-7.

Hypothalamic mapping of orexigenic action and Fos-like immunoreactivity following relaxin-3 administration in male Wistar rats.
Mcgowan BM, Stanley SA, White NE, et al. Am J Physiol Endocrinol Metab. 2007;292(3):E913-9.

Relaxin receptors in hepatic stellate cells and cirrhotic liver.
Bennett RG, Dalton SR, Mahan KJ, Gentry-nielsen MJ, Hamel FG, Tuma DJ. Biochem Pharmacol. 2007;73(7):1033-40.

Chronic intracerebroventricular administration of relaxin-3 increases body weight in rats.
Hida T, Takahashi E, Shikata K, et al. J Recept Signal Transduct Res. 2006;26(3):147-58.

Relaxin receptor expression in hepatic stellate cells and in cirrhotic rat liver tissue.
Bennett RG, Mahan KJ, Gentry-nielsen MJ, Tuma DJ. Ann N Y Acad Sci. 2005;1041:185-9.

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