Foods eating increase insulin level & proGIP and proglucagon. During fasting both GLP-1 and insulin secretion decrease. Conversely, glucagon secretion increases, further maintaining insulin secretion. The stimulated amino acids uptake and glucose production using alternative sources of energy, helping maintain normoglycemia and normal body weight. Increased intake of carbohydrates stimulates GLP-1 secretion and insulin secretion, both GLP-1 and insulin decrease glucagon secretion. In this scenario increased insulin level promote glucose uptake and storage, leading to weight gain and maintaining normal blood sugar levels.