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CGRP (Human)

Catalog No. 015-02

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Catalog #: 015-02

Size: 200 µg

Price: $94


Sequence:	Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2
Molecular Weight:	3789.35
Purity:	≥ 95%
Validation:	Exhibits correct molecular weight
Solubility:	Soluble in water
Storage:	Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Appearance:	White powder
Contents:	Each vial contains 200 µg of NET peptide.
Disulfide Bridge:	Disulfide bridge(s): Cys2-Cys7
Intra-Assay CV:	<10%
Inter-Assay CV:	<15%
Sample Extraction:
Standard Curve:

Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2.
Tam CW, Husmann K, Clark NC, et al. Circ Res. 2006;98(2):262-70.

Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue.
Linscheid P, Seboek D, Zulewski H, Keller U, Müller B. Endocrinology. 2005;146(6):2699-708.

Stress-induced suppression of the gonadotropin-releasing hormone pulse generator in the female rat: a novel neural action for calcitonin gene-related peptide.
Li XF, Bowe JE, Mitchell JC, Brain SD, Lightman SL, O'byrne KT. Endocrinology. 2004;145(4):1556-63.

The assessment of vasoactive properties of CGRP and adrenomedullin in the microvasculature: a study using in vivo and in vitro assays in the mouse.
Tam C, Brain SD. J Mol Neurosci. 2004;22(1-2):117-24.

Autocrine role of adrenomedullin in the human adrenal cortex.
Thomson LM, Kapas S, Carroll M, Hinson JP. J Endocrinol. 2001;170(1):259-65.

Complement factor H is a serum-binding protein for adrenomedullin, and the resulting complex modulates the bioactivities of both partners.
Pio R, Martinez A, Unsworth EJ, et al. J Biol Chem. 2001;276(15):12292-300.

Calcitonin gene-related peptide decreases expression of HLA-DR and CD86 by human dendritic cells and dampens dendritic cell-driven T cell-proliferative responses via the type I calcitonin gene-related peptide receptor.
Carucci JA, Ignatius R, Wei Y, et al. J Immunol. 2000;164(7):3494-9.

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Peptide Family

CGRP

Species

Human

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Available only to verified institutional research accounts for in vitro laboratory research and preclinical studies.

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