Verified institutional research accounts only. Supplied for in vitro laboratory research and preclinical studies.
Peptides
Relaxin 2 (Human) – 100µg
Catalog No. 035-62A
Catalog #: 035-62A
Size: 100 µg
Price: $475
| Sequence: | pGlu-Leu-Tyr-Ser-Ala-Leu-Ala-Asn-Lys-Cys-Cys-His-Val-Gly-Cys-Thr-Lys-Arg-Ser-Leu-Ala-Arg-Phe-Cys |
| B-Chain: | Asp-Ser-Trp-Met-Glu-Glu-Val-Ile-Lys-Leu-Cys-Gly-Arg-Glu-Leu-Val-Arg-Ala-Gln-Ile-Ala-Ile-Cys-Gly-Met-Ser-Thr-Trp-Ser |
| Molecular Weight: | 5963.06 |
| Purity: | ≥ 95% |
| Validation: | Exhibits correct molecular weight |
| Solubility: | Soluble in water |
| Storage: | Up to 6 months in lyophilized form at 0-5°C.
For best results, rehydrate just before use. |
| Appearance: | White powder |
| Contents: | Each vial contains 100 µg of NET peptide. |
| Disulfide Bridge: | Disulfide bridge(s): CysA10-CysA15, CysA11-CysB11, CysA24-CysB23 |
Relaxin in paraventricular nucleus contributes to sympathetic overdrive and hypertension via PI3K-Akt pathway.
Sun HJ, Chen D, Han Y, et al. Neuropharmacology. 2016;103:247-56.
H2 and H3 relaxin inhibit high glucose-induced apoptosis in neonatal rat ventricular myocytes.
Zhang X, Ma X, Zhao M, et al. Biochimie. 2015;108:59-67.
Relaxin affects cell organization and early and late stages of spermatogenesis in a coculture of rat testicular cells.
Pimenta MT, Francisco RA, Silva RP, Porto CS, Lazari MF. Andrology. 2015;3(4):772-86.
The positive inotropic effect of relaxin-2 in human atrial myocardium is preserved in end-stage heart failure: role of G(i)-phosphoinositide-3 kinase signaling.
Dschietzig T, Alexiou K, Kinkel HT, Baumann G, Matschke K, Stangl K. J Card Fail. 2011;17(2):158-66.
Relaxin stimulates osteoclast differentiation and activation.
Ferlin A, Pepe A, Facciolli A, Gianesello L, Foresta C. Bone. 2010;46(2):504-13.
Autoregulation of human relaxin-2 gene expression critically involves relaxin and glucocorticoid receptor binding to glucocorticoid response half-sites in the relaxin-2 promoter.
Dschietzig T, Bartsch C, Wessler S, Baumann G, Stangl K. Regul Pept. 2009;155(1-3):163-73.
