INSL3 / RLF (Human) - RIA Kit


Catalog #
RK-035-27 125 tubes $867

  • Protocol:
  • View/Download (PDF) - for reference only
  • Sample Preparation:
  • Suggested Procedure
  • Sample Extraction:
  • Recommended
  • Sensitivity: polaroid
    Data may differ slightly based on lot.
  • 60.4 pg/ml
  • Standard Range:
  • 10 - 1280 pg/ml
  • Cross Reactivity:
  • Peptide %
    Insulin-Like 3 (INSL-3) (Human) 100
    Insulin-Like 3 (INSL-3) (Mouse) 0
    Insulin (Human) 0
    Insulin-Like 4 (INSL-4) (Human) 0
    Insulin-Like 5 (INSL-5) (Human) 0
    Insulin-Like 6 (INSL-6) (Human) 0
    Insulin-Like 7 (INSL-7) (Human) 0
    C-peptide (Human) 0
    Amylin (Human) 0
    Glucagon (Human) 0
    GLP-1 (7-37) (Human) 0
    GLP-2 (Human) 0
    Ghrelin (Human)  0
    LH-RH (Human, Porcine, Rat) 0
    CGRP (Human) 0
    AGRP (83-132) –Amide (Human) 0

  • Radioactivity:
  • Each kit contains 1.5 µCi of Iodine 125.
  • Disclaimer:
  • This package conforms to the 49 CFR173.421 for expected radioactive material limited quantity, N.O.S. UN2910.
  • MSDS:
  • View/Download(PDF)

Expression of insulin-like 3 (INSL3) and differential splicing of its receptor in the ovary of rhesus macaques. 
Hanna CB, Yao S, Patta MC, Jensen JT, Wu X. Reprod Biol Endocrinol. 2010;8:150.

Insulin-like factor 3: a new circulating hormone related to luteinizing hormone-dependent ovarian hyperandrogenism in the polycystic ovary syndrome.
Gambineri A, Patton L, De iasio R, Palladoro F, Pagotto U, Pasquali R.  J Clin Endocrinol Metab. 2007;92(6):2066-73.

Intratesticular androgens and spermatogenesis during severe gonadotropin suppression induced by male hormonal contraceptive treatment.
Page ST, Kalhorn TF, Bremner WJ, Anawalt BD, Matsumoto AM, Amory JK. J Androl. 2007;28(5):734-41.

Elevated end-of-treatment serum INSL3 is associated with failure to completely suppress spermatogenesis in men receiving male hormonal contraception.
Amory JK, Page ST, Anawalt BD, Coviello AD, Matsumoto AM, Bremner WJ. J Androl. 2007;28(4):548-54.

Novel mutations involving the INSL3 gene associated with cryptorchidism.
El houate B, Rouba H, Sibai H, et al. J Urol. 2007;177(5):1947-51.

Testosterone gel combined with depomedroxyprogesterone acetate is an effective male hormonal contraceptive regimen and is not enhanced by the addition of a GnRH antagonist.
Page ST, Amory JK, Anawalt BD, et al. J Clin Endocrinol Metab. 2006;91(11):4374-80.

Changes in serum insulin-like factor 3 during normal male puberty.
Ferlin A, Garolla A, Rigon F, Rasi caldogno L, Lenzi A, Foresta C. J Clin Endocrinol Metab. 2006;91(9):3426-31.

Insulin-like factor 3 gene mutations in testicular dysgenesis syndrome: clinical and functional characterization.
Ferlin A, Bogatcheva NV, Gianesello L, et al. Mol Hum Reprod. 2006;12(6):401-6.

A novel circulating hormone of testis origin in humans.
Foresta C, Bettella A, Vinanzi C, et al. J Clin Endocrinol Metab. 2004;89(12):5952-8.

GREAT/LGR8 is the only receptor for insulin-like 3 peptide.
Bogatcheva NV, Truong A, Feng S, Engel W, Adham IM, Agoulnik AI. Mol Endocrinol. 2003;17(12):2639-46.