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Adrenomedullin (Human)

Quantity:

Catalog #
Size
Price
010-01 100 µg $211

Sequence:  ()
Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2
Disulfide bridge(s): Cys16-Cys21
  • Molecular Weight:
  • 6028.82
  • Purity:
  • ≥ 95%
  • Validation:
  • Exhibits correct molecular weight
  • Solubility:
  • Soluble in water
  • Storage:
  • Up to 6 months in lyophilized form at 0-5°C.
    For best results, rehydrate just before use.
    After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
  • Appearance:
  • White powder
  • Contents:
  • Each vial contains 100 µg of NET peptide.
  • MSDS:
  • View/Download(PDF)

Poly(lactic-co-glycolic) acid/nanohydroxyapatite scaffold containing chitosan microspheres with adrenomedullin delivery for modulation activity of osteoblasts and vascular endothelial cells.
Wang L, Li C, Chen Y, Dong S, Chen X, Zhou Y. Biomed Res Int. 2013;2013:530712.

Adrenomedullin expression in epithelial ovarian cancers and promotes HO8910 cell migration associated with upregulating integrin α5β1 and phosphorylating FAK and paxillin.
Deng B, Zhang S, Miao Y, et al. J Exp Clin Cancer Res. 2012;31:19.

Structure of micelle-bound adrenomedullin: a first step toward the analysis of its interactions with receptors and small molecules.
Pérez-castells J, Martín-santamaría S, Nieto L, et al. Biopolymers. 2012;97(1):45-53.

Intracellular proadrenomedullin-derived peptides decorate the microtubules and contribute to cytoskeleton function.
Sackett DL, Ozbun L, Zudaire E, et al. Endocrinology. 2008;149(6):2888-98.

Interaction of adrenomedullin and calcitonin gene-related peptide with the periodontal pathogen Porphyromonas gingivalis.
Allaker RP, Sheehan BE, Mcanerney DC, Mckay IJ. FEMS Immunol Med Microbiol. 2007;49(1):91-7.

Mechanisms of adrenomedullin antimicrobial action.
Allaker RP, Grosvenor PW, Mcanerney DC, et al. Peptides. 2006;27(4):661-6.

Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis.
Zudaire E, Martínez A, Garayoa M, et al. Am J Pathol. 2006;168(1):280-91.

Neuroendocrine profiling of humans receiving cardiac allografts.
Ogawa T, Veinot JP, Davies RA, et al. J Heart Lung Transplant. 2005;24(8):1046-54.

Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue.
Linscheid P, Seboek D, Zulewski H, Keller U, Müller B. Endocrinology. 2005;146(6):2699-708.

Adrenomedullin protects against myocardial apoptosis after ischemia/reperfusion through activation of Akt-GSK signaling.
Yin H, Chao L, Chao J. Hypertension. 2004;43(1):109-16.

Regulation of adrenomedullin secretion in cultured human skin and oral keratinocytes.
Kapas S, Tenchini ML, Farthing PM. J Invest Dermatol. 2001;117(2):353-9.

Autocrine role of adrenomedullin in the human adrenal cortex.
Thomson LM, Kapas S, Carroll M, Hinson JP. J Endocrinol. 2001;170(1):259-65.

Complement factor H is a serum-binding protein for adrenomedullin, and the resulting complex modulates the bioactivities of both partners.
Pio R, Martinez A, Unsworth EJ, et al. J Biol Chem. 2001;276(15):12292-300.

Effects of adrenomedullin on cyclic AMP formation and on relaxation in iris sphincter smooth muscle.
Yousufzai SY, Ali N, Abdel-latif AA. Invest Ophthalmol Vis Sci. 1999;40(13):3245-53.

Autocrine role for the endothelin-B receptor in the secretion of adrenomedullin.
Jougasaki M, Schirger JA, Simari RD, Burnett JC. Hypertension. 1998;32(5):917-22.

Neutral endopeptidase inhibition potentiates the natriuretic actions of adrenomedullin.
Lisy O, Jougasaki M, Schirger JA, Chen HH, Barclay PT, Burnett JC. Am J Physiol. 1998;275(3 Pt 2):F410-4.

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